A Chelsea újabb vereségével indult a forduló, majd nyert az Arsenal és a Manchester City. A Manchester United nyerte a Liverpool elleni rangadót
| 2015-09-12 13:45 | EVERTON Naismith 17, 22, 82 |
3-1 | CHELSEA Matic 36 |
| 2015-09-12 16:00 | CRYSTAL PALACE | 0-1 | MANCHESTER CITY Iheanacho 90 |
| 2015-09-12 16:00 | NORWICH CITY C.Jerome 35 Hoolahan 52 M.Jarvis 67 |
3-1 | BORNEMOUTH S.Cook 81 |
| 2015-09-12 16:00 | WEST BROMWICH | 0-0 | SOUTHAMPTON |
| 2015-09-12 16:00 | WATFORD Ighalo 59 piros: Behrami 64 |
1-0 | SWANSEA CITY |
| 2015-09-12 16:00 | ARSENAL Walcott 31 Giroud 85 |
2-0 | STOKE CITY |
| 2015-09-12 18:30 | MANCHESTER UNITED Blind 49 Ander Herrera 70 (11-es) Martial 86 |
3-1 | LIVERPOOL Benteke 84 |
| 2015-09-13 14:30 | SUNDERLAND | 0-1 | TOTTENHAM Mason 82 |
| 2015-09-13 17:00 | LEICESTER CITY De Laet 72 Vardy 82 Dyer 89 |
3-2 | ASTON VILLA Grealish 39 Carles Gil 63 |
| 2015-09-14 21:00 | WEST HAM Payet 9, 48 |
2-0 | NEWCASTLE UNITED |