Kikapott a Samp, a Genoa meg döntetlent játszott. Nyert a Roma, a Juve és a Fiorentina. Az Inter nyerte a milánói derbit.
| 2012-10-06 18:00 | CHIEVO Théréau 45+1 Di Michele 87 |
2:1 | SAMPDORIA Maresca 61 |
| 2012-10-06 20:45 | GENOA Borriello 52 |
1:1 | PALERMO Giorgi 14 |
| 2012-10-07 12:30 | AS ROMA Lamela 30 Bradley 62 |
2:0 | ATALANTA |
| 2012-10-07 15:00 | CATANIA Gómez 2 Bergessio 80 |
2:0 | PARMA piros: Y.Benalouane 69 |
| 2012-10-07 15:00 | FIORENTINA Jovetic 7 |
1:0 | BOLOGNA |
| 2012-10-07 15:00 | SIENA Calaio 45 |
1:2 | JUVENTUS Pirlo 14 Marchisio 85 |
| 2012-10-07 15:00 | TORINO | 0:1 | CAGLIARI Nené 74 (11-es) |
| 2012-10-07 15:00 | PESCARA | 0:3 | LAZIO Hernanes 5 Klose 25, 36 |
| 2012-10-07 20:45 | MILAN | 0:1 | INTER Samuel 3 piros: Nagatomo 48 |
| 2012-10-07 20:45 | NAPOLI Hamsik 30 Pandev 45 |
2:1 | UDINESE Pinzi 43 |